| Cohort Name |
Biomagnetic biomarkers for dementia |
| Cohort Acronym |
BioFIND |
| DOI |
Henson, R. (2020). BioFIND [Data set]. Dementias Platform UK. https://doi.org/10.48532/007000 |
| Study Overview |
Resting-state MEG data and T1 structural MRI data on ~160 MCI patients and ~160 healthy controls |
| #Subjects at Baseline |
324 |
| Institution Name |
University of Cambridge |
| Department Name |
MRC Cognition & Brain Sciences Unit |
| City |
Cambridge |
| Study/Database Website |
https://biofind-archive.mrc-cbu.cam.ac.uk/ |
| Principal Investigator (PI) |
Richard Henson |
| Key Study References |
Hughes, L.E., Henson, R.N., Pereda, E., Bruña, R., López-Sanz, D., Quinn, A.J., Woolrich, M.W., Nobre, K.C., Rowe, J.B., Maestú, R. & BioFIND Working Group (2019). Biomagnetic biomarkers for dementia: A pilot multicentre study with a recommended methodological framework for magnetoencephalography. Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring. Vaghari, D., Bruna R.,, Hughes, L., Nesbitt, D., Tibon, R., Rowe, J., Maestu, F. & Henson, R. (in prep). A multi-site, multi-participant magnetoencephalography resting-state dataset to study dementia: The BioFIND dataset. |
| Population Based Study? |
No |
| Family Based Study? |
No |
| Clinical based sample? |
Yes |
| Is there follow-up data available? |
Limited |
| Were participants included prior to development of dementia (may refer to controls only)? |
Yes |
| Were participants included prior to development of MCI (may refer to controls only)? |
Yes |
| How is data collected? |
Across several smaller studies conducted at MRC CBU in Cambridge and CTB in Madrid, Spain |
| Who carries out data collection? |
CBU and CTB |
| Does this take place in participants' homes or at a central location? |
In MEG and MRI labs at CBU and CTB |
| Do participants take part individually or are families/partners involved? |
Individually |
| Dementia cases ascertained as part of study: |
|
| How many times followed up? |
Occasionally, as part of Cambridge and Madrid Memory Clinics |
| Study start date |
2005 |
| Study end date |
ongoing |
| Is study ongoing? |
yes |
| Is study still recruiting? |
yes |
| Inclusion criteria |
MCI or age/sex matched healthy control |
| Exclusion criteria |
not MEG or MRI compatible |